Δημοσιεύσεις 2016

INTERACTION BETWEEN BETA-CATENIN AND EGFR EXPRESSION BY IMMUNOHISTOCHEMISTRY IDENTIFIES PROGNOSTIC SUBGROUPS IN EARLY HIGH-RISK TRIPLE NEGATIVE BREAST CANCER.  

Sotirios Lakis, Stefanos Dimoudis, Vassiliki Kotoula, Zoi Alexopoulou, Ioannis Kostopoulos, Triantafyllia Koletsa, Mattheos Bobos, Eleni Timotheadou, Irene Papaspirou, Ioannis Efstratiou, Gerasimos Aravantinos, Vasilios Karavasilis, Flora Zagouri, Helen Gogas, Evangelia Razis, George Pentheroudakis, Christos Christodoulou, Dimitrios Pectasides, George Fountzilas

Anticancer Res. 2016 May;36(5):2365-78.

MYC COPY GAIN, CHROMOSOMAL INSTABILITY AND PI3K ACTIVATION AS POTENTIAL MARKERS OF UNFAVOURABLE OUTCOME IN TRASTUZUMAB-TREATED PATIENTS WITH METASTATIC BREAST CANCER

Helen Gogas, Vassiliki Kotoula, Zoi Alexopoulou, Christos Christodoulou, Ioannis Kostopoulos, Mattheos Bobos, Georgia Raptou, Elpida Charalambous, Eleftheria Tsolaki, Ioannis Xanthakis, George Pentheroudakis, Angelos Koutras, Dimitrios Bafaloukos, Pavlos Papakostas, Gerasimos Aravantinos, Amanda Psyrri, Kalliopi Petraki, Dimitrios Pectasides, George Fountzilas

J Transl Med. 2016 May 17;14(1):136. doi: 10.1186/s12967-016-0883-z.

TP53 MUTATIONS AND PROTEIN IMMUNOPOSITIVITY MAY PREDICT FOR POOR OUTCOME BUT ALSO FOR TRASTUZUMAB BENEFIT IN PATIENTS WITH EARLY BREAST CANCER TREATED IN THE ADJUVANT SETTING

Fountzilas G, Giannoulatou E, Alexopoulou Z, Zagouri F, Timotheadou E, Papadopoulou K, Lakis S, Bobos M, Poulios C, Sotiropoulou M, Lyberopoulou A, Gogas H, Pentheroudakis G, Pectasides D, Koutras A, Christodoulou C, Papandreou C, Samantas E, Papakostas P, Kosmidis P, Bafaloukos D, Karanikiotis C, Dimopoulos MA, Kotoula V.

Oncotarget. 2016 May 31;7(22):32731-53. doi: 10.18632/oncotarget.9022.

TUMORS WITH HIGH-DENSITY TUMOR INFILTRATING LYMPHOCYTES CONSTITUTE A FAVORABLE ENTITY IN BREAST CANCER: A POOLED ANALYSIS OF FOUR PROSPECTIVE ADJUVANT TRIALS.

Kotoula V, Chatzopoulos K, Lakis S, Alexopoulou Z, Timotheadou E, Zagouri F, Pentheroudakis G, Gogas H, Galani E, Efstratiou I, Zaramboukas T, Koutras A, Aravantinos G, Samantas E, Psyrri A, Kourea H, Bobos M, Papakostas P, Kosmidis P, Pectasides D, Fountzilas G

Oncotarget. 2016 Jan 26;7(4):5074-87. doi: 10.18632/oncotarget.6231.

EFFECTS OF TP53 AND PIK3CA MUTATIONS IN EARLY BREAST CANCER: A MATTER OF CO-MUTATION AND TUMOR INFILTRATING LYMPHOCYTES

Vassiliki Kotoula, Vasilios Karavasilis, Flora Zagouri, George Kouvatseas, Eleni Giannoulatou, Helen Gogas, Sotiris Lakis, George Pentheroudakis, Mattheos Bobos, Kyriaki Papadopoulou, Eleftheria Tsolaki, Dimitrios Pectasides, Georgios Lazaridis, Angelos Koutras, Gerasimos Aravantinos, Christos Christodoulou, Pavlos Papakostas, Christos Markopoulos, George Zografos, Christos Papandreou, George Fountzilas

Breast Cancer Res Treat. 2016 Jul;158(2):307-21. doi: 10.1007/s10549-016-3883-z.

TUMOR INFILTRATING LYMPHOCYTES AFFECT THE OUTCOME OF PATIENTS WITH OPERABLE TRIPLE-NEGATIVE BREAST CANCER IN COMBINATION WITH MUTATED AMINO ACID CLASSES.

Kotoula V, Lakis S, Vlachos IS, Giannoulatou E, Zagouri F, Alexopoulou Z, Gogas H, Pectasides D, Aravantinos G, Efstratiou I, Pentheroudakis G, Papadopoulou K, Chatzopoulos K, Papakostas P, Sotiropoulou M, Nicolaou I, Razis E, Psyrri A, Kosmidis P, Papadimitriou C, Fountzilas G.

PLoS One. 2016 Sep 29;11(9):e0163138. doi: 10.1371/journal.pone.0163138.

Disease evolution and heterogeneity in bilateral breast cancer.

Fountzilas E, Kotoula V, Zagouri F, Giannoulatou E, Kouvatseas G, Pentheroudakis G, Koletsa T, Bobos M, Papadopoulou K, Samantas E, Demiri E, Miliaras S, Christodoulou C, Chrisafi S, Razis E, Fostira F, Pectasides D, Zografos G, Fountzilas G.

Am J Cancer Res. 2016 Nov 1;6(11):2611-2630

HER FAMILY PROTEIN EXPRESSION IN A GREEK POPULATION WITH GASTRIC CANCER. A RETROSPECTIVE HELLENIC COOPERATIVE ONCOLOGY GROUP STUDY

T. Makatsoris, A.C. Tsamandas, A. Strimpakos, Z. Alexopoulou, D. Dionysopoulos, S. Pervana, A. Konstantara, P. Papakostas, E. Samantas, G. Rallis, A. Dimou, G. Pentheroudakis, K. Papaparaskeva, A. Psyrri, K.T. Kalogeras, K. Syrigos, C.D. Scopa, G. Fountzilas

Anticancer Research 36: 1581-1590 (2016)

Expression Patterns of Growth and Survival Genes with Prognostic Implications in Advanced Pancreatic Cancer.

Pectasides D, Kotoula V, Papaxoinis G, Alexopoulou Z, Dervenis C, Samantas E, Papaparaskeva K, Charalambous E, Gkakou C, Agalianos C, Kalogeras KT, Pentheroudakis G, Fountzilas G.

Anticancer Res. 2016 Dec;36(12):6347-6356.

Therapies in the pipeline for small-cell lung cancer.

Romanidou O, Imbimbo M, Mountzios G, Abidin A, Morgillo F, Califano R.

Br Med Bull. 2016 Sep;119(1):37-48.

MYC COPY GAIN, CHROMOSOMAL INSTABILITY AND PI3K ACTIVATION AS POTENTIAL MARKERS OF UNFAVOURABLE OUTCOME IN TRASTUZUMAB-TREATED PATIENTS WITH METASTATIC BREAST CANCER.

Gogas H, Kotoula V, Alexopoulou Z, Christodoulou C, Kostopoulos I, Bobos M, Raptou G, Charalambous E, Tsolaki E, Xanthakis I, Pentheroudakis G, Koutras A, Bafaloukos D, Papakostas P, Aravantinos G, Psyrri A, Petraki K, Kalogeras KT, Pectasides D, Fountzilas G.

J Transl Med. 2016 May 17;14(1):136. doi: 10.1186/s12967-016-0883-z.